Silence any
gene, anywhere
We deliver breakthrough receptor-targeted RNA medicines with cutting-edge physics-aware deep learning, single cell biology, and high-throughput chemistry
AI-powered drug design & delivery platform
Reach more targets, reach more diseases
Our proprietary platform, Connexa, designs RNA therapeutics that can target any cell type, unleashing the full potential of gene silencing in the treatment of chronic diseases
The Connexa Difference
Reach the Right Target
Unlock treatments for conditions of the heart, lungs, kidneys, muscle, small intestine, blood cells, and brain
Using the Right Delivery Vehicle
AI-enabled design of delivery vehicles with all required properties means a rapid and de-risked path to in vivo
With the Right Payload
Maximize efficacy from the start by rationally designing, co-selecting, and
co-optimizing delivery ligands with specific RNA payloads
Why silencing?
Gene silencing is a better way to inhibit disease-causing proteins
- Redosable
Non-immunogenic
- Safe
High cell and gene specificity
- Low Cost
Simple manufactoring process
- Convenient
Subcutaneous administration
- Universal
Any gene can be silenced
- Long Duration
Up to 6 month duration between doses
Small-molecule medicines bind problematic proteins to inhibit activities
RNA medicines prevent
problematic proteins from being produced by silencing their genes
problematic proteins from being produced by silencing their genes
vs
Partner to create revolutionary RNA medicines
Leverage the only platform built to unlock therapeutic access of RNA to all key cell types
Let's talk